Purine and carboline alkaloids from ascidian Symplegma oceania.
- Author:
Shu-Ming ZHAO
1
;
Ya-Nan LU
;
Xiao-Qing TIAN
;
Qiao YANG
;
Hui-Juan YU
;
Cheng-Qi FAN
Author Information
1. Key Laboratory of East China Sea & Oceanic Fishery Resources Exploitation and Utilization, Ministry of Agriculture, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China.
- Publication Type:Journal Article
- MeSH:
Alkaloids;
chemistry;
Animals;
Carbolines;
chemistry;
Magnetic Resonance Spectroscopy;
Molecular Structure;
Purines;
chemistry;
Urochordata;
chemistry
- From:
China Journal of Chinese Materia Medica
2013;38(7):1018-1020
- CountryChina
- Language:Chinese
-
Abstract:
Five purine and carboline alkaloids were isolated from the methanol extract of the ascidian Symplegma oceania. Classic chromatographies including preparative HPLC were used for isolation and purification of the compounds. The structures were established as 6-methoxy-7-methyl-8-oxoguanine (1), 2-methylimino-3-methyl-6-methylamino- 9H-purine (2), 1,2,3,4-tetrahydro-betacarboline (3), 1,2,3,4-tetrahydro-1-methyl-beta-carboline (4) and 1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid (5) by comparison the spectroscopic data (MS, 1H, 13C-NMR) with those reported in the literatures. Compounds 2-5 were reported from the the genus Symplegma for the first time. The purine and carboline were the major alkaloid types of S. oceania.
