Advance in studies on anti-tumor activity of polysaccharides in latest five years.
- Author:
Jun LIN
1
;
Ping LI
;
Kao-Shan CHEN
Author Information
1. Department of Pharmacology, Wannan Medical College, Wuhu 241000, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Antineoplastic Agents;
pharmacology;
therapeutic use;
Apoptosis;
drug effects;
Cell Proliferation;
drug effects;
Humans;
Immunity;
drug effects;
Immunologic Factors;
pharmacology;
therapeutic use;
Neoplasms;
drug therapy;
immunology;
metabolism;
Polysaccharides;
pharmacology;
therapeutic use;
Signal Transduction;
drug effects
- From:
China Journal of Chinese Materia Medica
2013;38(8):1116-1125
- CountryChina
- Language:Chinese
-
Abstract:
Polysaccharides widely exist in animals, plants, microorganisms, and possess various biological activities including anti-tumor, anti-virus, anti-oxidant and immunomodulatory. Polysaccharides shows notable anti-tumor activity and less toxicity, and becomes a hotspot in the studies of anti-tumor drugs. Therefore, there is huge potential for developing polysaccharides into a novel antitumor medicine. This article summarized polysaccharides derived from animals, plants, microorganisms which have significant antitumor effect in the latest 5 years; findings indicate that polysaccharides show the anti-tumor effect directly by inducing tumor cell apoptosis and indirectly as an immunoenhancement. This article also looks into the future of studies on anti-tumor activity of polysaccharides.
