Chemical constituents from leaves of Evodia lepta.
- Author:
He-Lin WEI
1
;
Si-Xiang ZHOU
;
Yong JIANG
;
Yue-Lin SONG
;
Jun LI
;
Peng-Fei TU
Author Information
1. States Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.
- Publication Type:Journal Article
- MeSH:
Evodia;
chemistry;
Magnetic Resonance Spectroscopy;
Plant Extracts;
chemistry;
isolation & purification;
Plant Leaves;
chemistry
- From:
China Journal of Chinese Materia Medica
2013;38(8):1193-1197
- CountryChina
- Language:English
-
Abstract:
To explore the alternative material for the stems of Evodia lepta used in clinic, the leaves extract of E. lepta was chemically investigated by silica gel, Sephadex LH-20, ODS column chromatographies, and preparative HPLC and the structures of the compounds were identified mainly by spectroscopic methods. Ten known compounds 4-hydroxy-4, 7-dimethyl-1-tetralone (1), (6R, 7E) -4, 7-megastigmadien-3, 9-dione (2), 4-megastigmen-3, 9-dione (3), formononetin (4), daidzein (5), oroxylin A (6), wogonin (7), 5, 7-dihydroxy-3, 4'-dimethoxyflavone (8), N-trans-coumaroyltyranine (9) and (E) -p-hydroxycinnamic acid (10), have been obtained and identified. All these compounds were isolated from this species for the first time. The results revealed that there is a considerate chemical difference between the stems and leaves of E. lepta.
