Successful Treatment of Lupoid Cutaneous Leishmaniasis with Glucantime and Topical Trichloroacetic Acid (A Case Report).
10.3347/kjp.2008.46.3.175
- Author:
Mohamad Ali NILFOROUSHZADEH
1
;
Giti SADEGHIAN
;
Fariba JAFFARY
;
Hengameh ZIAEI
;
Liela SHIRANI-BIDABAD
;
Parvin MAHZONI
Author Information
1. Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. Sadeghian@sdlrc.mui.ac.ir
- Publication Type:Case Report
- Keywords:
Leishmanis tropica;
cutaneous leishmaniasis;
trichloroacetic acid
- MeSH:
Administration, Topical;
Adult;
Antiprotozoal Agents/administration & dosage/*therapeutic use;
Humans;
Leishmaniasis, Cutaneous/*drug therapy/pathology;
Male;
Meglumine/*therapeutic use;
Organometallic Compounds/*therapeutic use;
Trichloroacetic Acid/administration & dosage/*therapeutic use
- From:The Korean Journal of Parasitology
2008;46(3):175-177
- CountryRepublic of Korea
- Language:English
-
Abstract:
Lupoid leishmaniasis is a unique form of cutaneous leishmaniasis characterized by unusual clinical features and a chronic relapsing course, mostly caused by infection with Leishmania tropica. In this clinical form, 1-2 yr after healing of the acute lesion, new papules and nodules appear at the margin of the remaining scar. Herein, we describe a case of this clinical form that was resistant to 2 courses of treatments: systemic glucantime and then a combination therapy with allopurinol and systemic glucantime. However, marked improvement was seen after a combination therapy with topical trichloroacetic acid solution (50%) and systemic glucantime, and there were no signs of recurrence after 1 yr of follow-up.
