Treatment of Uncomplicated Male Gonococcal Urethritis with Ofloxacin.
- Author:
Tchae Sik NAM
;
Young Tae KIM
;
Joong Hwan KIM
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
Gonococcal urethritis;
Ofloxacin
- MeSH:
Gonorrhea;
Humans;
Korea;
Male*;
Ofloxacin*;
Public Health;
Seoul;
Urethritis*
- From:Korean Journal of Dermatology
1988;26(6):867-873
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Ofloxacin, one of the new quinolone derivatives, is found to be highly effective against both PPNG and non-PPNG urethritis. The objective of this trial was to establish the efficacy of two ofloxacin regimens in the treatment of uncomplicated male gonococcal urethritis. A total of 138 patients with uncomplicated gonococcal urethritis seen at the VD Clinic, Choong-Ku Public Health Center, in Seoul in the period of March Jun 1988, were subjected to this study. The patients were divided randomly into two groups and assigned to one of two treatment regimens of afloxacin, 400mg, PO and 200mg, PO, twice a day for 2 days. No failure case was seen in both groups. Both of these ofloxacin regimens were found to be highly effective and safe in the treatment of gonococcal urethrithis. It is suggested that, because of high rate of PPNGs among circulating N. gonorrhoeae, they can be recommended as the first line treatment for gonorrhea in Korea.
