A Case of Pemphigus Vegetans of Neumann.
- Author:
Sung Hun KIM
;
Soo Gyoung HUR
;
Young Ho WON
;
Inn Ki CHUN
;
Young Pio KIM
- Publication Type:Case Report
- Keywords:
Neumann type;
Pemphigus vegetans
- MeSH:
Adult;
Biopsy;
Dapsone;
Eosinophils;
Epidermis;
Female;
Fluorescent Antibody Technique, Direct;
Fluorescent Antibody Technique, Indirect;
Genitalia;
Humans;
Immunoglobulin G;
Papilloma;
Pemphigus*;
Skin;
Tuberculosis, Pulmonary
- From:Korean Journal of Dermatology
1988;26(6):901-904
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We experienced a 40-year-old female patient who had vegetating plaques, erosions and a few vesicles on the external genitalia and the oral mucasa, assoeiated with pulmonary tuberculosis. On the skin biopsy specimen of the vegetating plaque, it showed acanthoais, papillomatosis, downward proliferation of the epidermis and eosinophilic microabacess in the epidermis. Direct immunofluorescence of the perilesional skin revealed deposition of IgG, Cq, Cs and C on the intercellular substance of the epidermis. Indirect immunofluorescence disclosed IgCi auto antibody(1: 320) positive to the inter ellular substance of the normal human back skin. The skin lesion had impraved with dapsone therapy.
