Systematic review of effectiveness and safety of pudilan Xiaoyan oral liquid in treating pediatric suppurative tonsilitis.
10.19540/j.cnki.cjcmm.2017.0045
- Author:
Li-Ling BIAN
1
;
Feng-Wen WANG
1
;
Yuan YANG
1
;
Li ZHANG
2
;
Chun-Xiang LIU
3
;
Jun-Hua ZHANG
3
;
Wen-Ke ZHENG
3
Author Information
1. Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
2. Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China.
3. Centre for Evidence-based Medicine Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
- Publication Type:Journal Article
- Keywords:
Pudilan;
randomized controlled trial;
suppurative tonsillitis;
systematic review
- From:
China Journal of Chinese Materia Medica
2017;42(8):1482-1488
- CountryChina
- Language:Chinese
-
Abstract:
The review aims to assess the effectiveness and safety Pudilan Xiaoyan oral liquid in treating pediatric suppurative tonsillitis systematically through searching relevant electronic database and collecting relevant literature. Meta-analysis was performed with the RevMan 5.3 software. Eighteen RCTs of 1 883 patients of pediatric suppurative tonsillitis were included. Meta-analysis showed that： compared with the application of antibiotics alone, combined with Pudilan can effectively improve the treatment of pediatric suppurative tonsillitis in efficacy rate and shorten the time of recovering normal temperature, the time of tonsil purulent discharge and can also reduce the extinction time of sore throat, antiadoncus or congestion subsided and appetite recovery. There was no severe adverse reaction during the treatment. Compared with the application of antibiotics alone, combined with Pudilan may be more effective and safe in the treatment of pediatric suppurative tonsillitis, which can not be strongly proved at present for lack of studies with high quality.
