Some clinical manifestations and immune tests for SLE patients treated in the Allergy - Immune Department of Bach Mai Hospital
- Author:
Anh Tram Hoang
- Publication Type:Journal Article
- Keywords:
systemic lupus erythematosus
- MeSH:
Lupus Erythematosus, Systemic;
Therapy
- From:Journal of Medical Research
1998;8(4):27-35
- CountryViet Nam
- Language:Vietnamese
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Abstract:
Systemic lupus erythematosus (SLE) is an autoimmune disease involving multiple organ systems that is characterized by the occurrence of antibodies directed against antigens. In this study, we mention 2 matters as following: (1) General conclusion on clinical manifestation and subjects of SLE patients treated in the Allergy-Immune Department of Bachmai Hospital from 1996-2000. (2) The role of immune tests for SLE patients, especially Combs and erythrocytic existing tests for SLE patients with anemia. We study 438 patients with clinical manifestation and subsets, researched document of 418 patients and carried out Combs and erythrocytic existing tests in 20 SLE patients treated in Allergy-Immune Department of Bachmai hospital. SLE are found mainly in woman (93.6%), concentrating in the child-bearing age. Hematological disorders (83.8%), "butterfly" rashes (81.9%), arthritis (81.2%) and renal damages (78.5%) are common symptoms. Positive nuclear antibodies occur in 76.3% of patients, antibodies to DNA in 60.5% and LE cell in 40.9%. The rater of 50% of patients with positive Combs test and 55% of patients with damaged erythocytic membranes have played an important role in demonstrating the hemolytic mechanism in SLE patients.
