The Case Report of a Child with High-Risk Acute Lymphoblastic Leukemia, Treated with Allogenic Peripheral Blood Stem Cell Transplantation.
- Author:
Jun GOH
;
Ji Hyun OH
;
Hyun Sang CHO
;
Dug Ha KIM
;
Chong Young PARK
- Publication Type:Case Report
- Keywords:
Allogenic peripheral blood stem cell transplantation
- MeSH:
Blood Platelets;
Bone Marrow;
Child*;
Female;
Graft vs Host Disease;
Humans;
Leukemia;
Neutrophils;
Peripheral Blood Stem Cell Transplantation*;
Precursor Cell Lymphoblastic Leukemia-Lymphoma*;
Siblings;
Tissue Donors
- From:Journal of the Korean Pediatric Society
2000;43(11):1505-1508
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Allogenic peripheral blood stem cell transplantation could be used instead of allogenic bone marrow in treatment of leukemia in children. This 10-year-old female patient with high-risk acute lymphoblastic leukemia received a myeloablative regimen followed by allogenic peripheral blood stem cell transplantation from an HI A-identical sibling donor. Neutrophil recovery to greater than 500/pL occurred at day 11 and platelets recovered to greater than 20,000/pL at day 13. Allogenic peripheral blood stem cell transplantation can be performed safely and may result in a rapid neutrophil and platelet engraftment, without any apparent increased risk of acute graft versus host disease.
