The application progress of human urine derived stem cells in bone tissue engineering.
10.3760/cma.j.issn.0529-5815.2016.04.018
- VernacularTitle:人尿源干细胞及其在骨组织工程中应用的研究进展
- Author:
Peng GAO
1
;
Dapeng JIANG
;
Zhaozhu LI
Author Information
1. Department of Pediatric Surgery, Harbin Children's Hospital, Harbin 150010, China.
- Publication Type:Journal Article
- MeSH:
Bone and Bones;
Cell Differentiation;
Humans;
Mesenchymal Stromal Cells;
Stem Cells;
cytology;
Tissue Engineering;
Urine;
cytology
- From:
Chinese Journal of Surgery
2016;54(4):317-320
- CountryChina
- Language:Chinese
-
Abstract:
The research of bone tissue engineering bases on three basic directions of seed cells, scaffold materials and growth information. Stem cells have been widely studied as seed cells. Human urine-derived stem cell (hUSC) is extracted from urine and described to be adhesion growth, cloning, expression of the majority of mesenchymal stem cell markers and peripheral cell markers, multi-potential and no tumor but stable karyotype with passaging many times. Some researches proposed that hUSC might be a new source of seed cells in tissue engineering because of their invasive and convenient obtention, stable culture and multiple differentiation potential.
