Risk factors of renal failure in the early post-liver transplantation period.
- Author:
Feng-xue ZHU
1
;
Chun-jun LIU
;
Ji-ye ZHU
;
Guang-ming LI
;
Lei HUANG
;
Dong WANG
;
Jie GAO
;
Zhi-min ZHENG
;
Xi-sheng LENG
Author Information
- Publication Type:Journal Article
- MeSH: Acute Kidney Injury; epidemiology; etiology; Adolescent; Adult; China; epidemiology; Creatinine; blood; Female; Humans; Liver Cirrhosis; surgery; Liver Transplantation; adverse effects; Male; Middle Aged; Prothrombin; metabolism; Risk Factors
- From: Chinese Journal of Hepatology 2005;13(3):168-170
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the risk factors of renal failure in the early post-liver transplantation period.
METHODS92 consecutive liver transplantation cases were reviewed and a multi-factor analysis of presumed risk factors of early post-transplantation period renal failure was conducted. The factors analyzed were total bilirubin level, prothrombin activity, onset of structural renal disease, onset of gastrointestinal hemorrhage, whether the patient underwent large-volume paracentesis, or underwent plasmapheresis therapy, needed renal replacement therapy, the operation method used, the bleeding volume during operation and the immunosuppressive agents used.
RESULTSOf the 92 patients, 29 (31.5%) developed acute renal failure (ARF) in the early postoperative period. Multi-factor analysis revealed a high pre-transplantation serum creatinine level and low prothrombin activity as risk factors for development of ARF.
CONCLUSIONARF is a frequent medical complication after liver transplantation. A high pre-transplantation serum creatinine level and low prothrombin activity are risk factors of its development.
