Triterpenoid saponins of Alternanthera philoxeroides (Mart.) Griseb.
- Author:
Qing-lan GUO
1
;
Bin LI
;
Jian LI
;
Jing-jing LI
;
Li-ying XIA
;
Jun-xing DONG
Author Information
1. Beijing Institute of Radiation Medicine, Beijing 100850, China.
- Publication Type:Journal Article
- MeSH:
Amaranthaceae;
chemistry;
Antiviral Agents;
chemistry;
isolation & purification;
pharmacology;
Hep G2 Cells;
Hepatitis B virus;
drug effects;
Humans;
Molecular Structure;
Oleanolic Acid;
analogs & derivatives;
chemistry;
isolation & purification;
pharmacology;
Plants, Medicinal;
chemistry;
Saponins;
chemistry;
isolation & purification;
pharmacology;
Triterpenes;
chemistry;
isolation & purification;
pharmacology
- From:
Acta Pharmaceutica Sinica
2011;46(4):428-431
- CountryChina
- Language:Chinese
-
Abstract:
In order to find the anti-virus constituents of Alternanthera philoxeroides (Mart.) Griseb, the investigation was carried out. The paper reported the five triterpenoid saponins isolated from n-BuOH fraction: 3-O-beta-D-glucopyranosyl (1-->3)-O-[beta-D-glucopyranosyl-oleanolic acid]-28-O-beta-D-glucuronopyranoside (1), oleanolic acid-3-O-beta-D-glucuronopyranoside (calenduloside E, 2), oleanolic acid-3-O-beta-D-glucopyranosyl-28-Obeta-D-glucopyranosyl ester (chikusetsusaponin-IVa, 3), 3-O-(6'-O-butyl-beta-D-glucuronopyranosyl)-oleanolic acid-28-O-beta-D-glucopyranosyl ester (4) and hederagenin-3-O-beta-D-glucuronopyranoside (HN-sapoins K, 5). 1 is a new compound, saponins 4 and 5 were isolated from the plant for the first time.
