Investigation on pattern and methods of quality control for Chinese materia medica based on dao-di herbs and bioassay - bioassay for Coptis chinensis.
- Author:
Dan YAN
1
;
Xiao-he XIAO
Author Information
1. China Military Institute of Chinese Materia Medica, 302 Military Hospital of China, Beijing 100039, China.
- Publication Type:Journal Article
- MeSH:
Berberine;
isolation & purification;
pharmacology;
Berberis;
chemistry;
Biological Assay;
methods;
Cluster Analysis;
Coptis;
chemistry;
Drugs, Chinese Herbal;
chemistry;
pharmacology;
standards;
Escherichia coli;
drug effects;
Materia Medica;
standards;
Phellodendron;
chemistry;
Plants, Medicinal;
chemistry;
Quality Control
- From:
Acta Pharmaceutica Sinica
2011;46(5):568-572
- CountryChina
- Language:Chinese
-
Abstract:
Establishment of bioassay methods is the technical issues to be faced with in the bioassay of Chinese materia medica. Taking the bioassay of Coptis chinensis Franch. as an example, the establishment process and application of the bioassay methods (including bio-potency and bio-activity fingerprint) were explained from the aspects of methodology, principle of selection, experimental design, method confirmation and data analysis. The common technologies were extracted and formed with the above aspects, so as to provide technical support for constructing pattern and method of the quality control for Chinese materia medica based on the dao-di herbs and bioassay.
