Study on the diagnostic test with C-reactive protein in elderly patients with infections.
- Author:
Xiao-ling HU
1
;
Lei WANG
;
Wen YANG
;
Wei YU
;
Xiao-hua YUE
;
Yu-hui LIU
;
Rong CHU
;
Yu WANG
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Biomarkers; analysis; C-Reactive Protein; analysis; Diagnostic Tests, Routine; Female; Humans; Male; Middle Aged; Pneumonia; diagnosis; Respiratory Tract Infections; diagnosis; Urinary Tract Infections; diagnosis
- From:Chinese Journal of Epidemiology 2003;24(4):304-306
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the value of C-reactive protein (CRP) to diagnostic test in elderly patients with infections.
METHODSC-reactive protein were investigated in 142 elderly patients with infections and 216 elderly patients without. CRP 7 - 20, 21 - 40 and 41 - 60 mg/L were stratified, the index of diagnostic test counted.
RESULTSConcentrations of CRP in patients with different diseases were upper respiratory tract infection 36.9 mg/L +/- 28.9 mg/L, acute bronchitis 30.1 mg/L +/- 28.1 mg/L, pneumonia 55.9 mg/L +/- 32.9 mg/L, urinary infection 49.0 mg/L +/- 27.6 mg/L and enteritis 39.3 mg/L +/- 35.6 mg/L. They were all higher than those in control group (5.2 mg/L +/- 2.9 mg/L, P < 0.001). Stratified analysis disclosed that the specificity of CRP was 83.3% - 99.0% for diagnostic infection disease. The positive likelihood ratio (LR) of 7 - 20, 21 - 40 and 41 - 60 mg/L were 3.6, 27.0 and 128.0, respectively.
CONCLUSIONC-reactive protein was an important marker to diagnose elderly patients with infections.
