A Meta-analysis on the relations between Helicobacter pylori infection and chronic urticaria
10.3760/cma.j.issn.0254-6450.2014.03.022
- VernacularTitle:幽门螺杆菌感染与慢性荨麻疹相关性的Meta分析
- Author:
Lude TANG
1
;
Yanjun ZHANG
;
Xiaomeng GAO
;
Rui DONG
;
Xifeng ZHANG
;
Hongxi GU
;
Qinglong SHANG
Author Information
1. 150081,哈尔滨医科大学微生物学教研室
- Keywords:
Helicobacter pylori;
Chronic urticaria;
Meta-analysis
- From:
Chinese Journal of Epidemiology
2014;35(3):317-321
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between Helicobacter pylori (HP) infection and the development of chronic urticaria.Methods Published case-control studies which concerned HP infection related chronic urticaria were searched in Wanfang,CNKI,CQVIP Chinese databanks and PubMed.Meta-analysis was applied to analyze the pooled odds ratio (OR) and 95％ confidence interval (CI).Results 37 studies which comprised 2 909 cases of chronic urticaria and 1 873 persons served as controls were enrolled.When compared with the controls,HP infection significantly increased the risk of chronic urticaria development with a pooled OR of 3.20 (95％CI:2.31-4.43).Results from Meta-regression analyses showed that the distribution of residential areas and detection method being used were potential influential factors.Conclusion HP infection seemed to be associated with an increased risk of developing the chronic urticaria.
