Characterization of antimicrobial resistances and molecular characteristics of Salmonella isolates from the pork production chain in Sichuan province, 2010-2011.

Xinfeng Han; Shuliang Liu; Xiaogang Hou; Xun Chen; Zhen Peng; Dongmei Zhu

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Characterization of antimicrobial resistances and molecular characteristics of Salmonella isolates from the pork production chain in Sichuan province, 2010-2011.

Author: Xinfeng HAN ¹ ; Shuliang LIU ² ; Xiaogang HOU ¹ ; Xun CHEN ¹ ; Zhen PENG ¹ ; Dongmei ZHU ¹
Author Information

1. College of Food Science, Sichuan Agricultural University, Ya'an 625014, China.
2. College of Food Science, Sichuan Agricultural University, Ya'an 625014, China. Email: lsliang999@163.com.
Publication Type:Journal Article
MeSH: Animals; Drug Resistance, Bacterial; Meat; microbiology; Salmonella; drug effects; isolation & purification; Swine
From: Chinese Journal of Epidemiology 2014;35(5):519-523
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo investigate the antimicrobial resistance and resistance profiles of Salmonella isolates, from the pork production chain in several districts of Sichuan province and to determine the correlation between serotype and the pulse field gel electrophoresis (PFGE) patterns.
METHODSFrom 2010 to 2011, a total of 112 Salmonella isolates from pork production chain were examined for their antimicrobial susceptibility, using the micro-dilution method against 10 antimicrobial agents.
RESULTSwere assessed by the standard by the Clinical and Laboratory Standards Institute (CLSI, 2010). In addition, PFGE patterns were investigated among the Salmonella strains from different sources, under different serovars and antimicrobial profiles.
RESULTSFor Salmonella isolated from the pork production chain, resistance to tetracycline (89.29%) was frequently observed. Many isolates were resistant to spectinomycin (36.61%), trimethoprim/sulfamethoxazole (35.71%), nalidixic acid (33.93%) and ampicillin (24.11%), but all of the isolates were susceptible to ceftiofur. 33.93% of the isolates were multi-drug resistant. Salmonella isolates from the pork production chain had 19 antibiotic resistance profiles. Totally, 34 PFGE patterns were detected among 74 Salmonella isolates from the pork production chain, with the PFGE patterns of the 74 Salmonella isolates sharing 40% to 100% similarities.
CONCLUSIONThe antimicrobial resistances of the Salmonella isolates were commonly detected from the pork production chain in Sichuan province suggesting that Salmonella might horizontally spread from food animals to retail meat products.