Synthesis of derivatives of N-propylpiononate and investigation on biological effects
- Author:
Thuy Minh Pham
- Publication Type:Journal Article
- Keywords:
synthesis
- MeSH:
Chemical synthesis;
Analogs & derivatives
- From:Pharmaceutical Journal
1999;282(10):17-19
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
From the essential oil of turpentive, the author have separated pinene. Some derivatives e.g. pinonic acid, oxypinocamphon and n-propyl pinonat were synthesized. 7 derivatives such as hydrazone, semicarbazone, thiosemicarbazone, 2,4 dinitrophenyl hydrazone and isonicotionyl hydrazone were prepared. The structures of the obtained products were characterized by elemental analyses and spectral methods (IR, UV). The biological activities of the products such as antibacterial and antifungal were tested. The results indicated that these compounds possessed biological activities, especially antibacterial activity.