Expression of CIC-5 in rat tooth germ development.

Author: Jin HOU ¹ ; Xiao-hong DUAN ; Zhen-qiang SI-TU
Author Information

1. Department of Oral Biology, School of Stomatology, The Fourth Military Medical University, Xi'an, China.
Publication Type:Journal Article
MeSH: Ameloblasts; Animals; Odontogenesis; RNA, Messenger; Rats; Tooth Germ
From: West China Journal of Stomatology 2007;25(5):444-453
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo determine the expression and possible function of CIC-5 during the rat tooth germ development.
METHODSIsolated total mRNA and protein from the rat tooth germs which were at different stages of development. RT-PCR and Western blot were used to investigate the mRNA and protein expression of the CIC-5 in the rat tooth germ.
RESULTSThe mRNA and protein of CIC-5 expressed in the late bell stage, but undetected inThe mRNA and protein of CIC-5 expressed in the late bell stage, but undetected in the early or middle bell stage.
CONCLUSIONThese results showed the spatial temporal distribution of expression of CIC-5 during the different stages of the rat tooth germ development and suggested that it might contribute to the rat tooth germ development.