Clinical Analysis of Patients with Ruptured Cerebral Aneurysms associated with Polycystic Kidney Disease.
- Author:
Hoon KIM
1
;
Jae Whan LEE
;
Tae Hyung KWON
;
Seung Kon HUH
;
Kyu Chang LEE
Author Information
1. Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Republic of Korea. leejw@yumc.yonsei.ac.kr
- Publication Type:Original Article
- Keywords:
Cerebral aneurysm;
Polycystic kidney
- MeSH:
Aneurysm;
Anterior Cerebral Artery;
Carotid Artery, Internal;
Follow-Up Studies;
Humans;
Hypertension;
Intracranial Aneurysm*;
Microsurgery;
Middle Cerebral Artery;
Polycystic Kidney Diseases*;
Retrospective Studies;
Subarachnoid Hemorrhage
- From:Korean Journal of Cerebrovascular Surgery
2007;9(3):212-215
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: This study is to define the clinical characteristics and formulate the management strategies of the patients with ruptured cerebral aneurysms associated with polycystic kidney diseases (PKD). METHODS: During the past 30 years, among of 3,013 patients who were treated with intracranial aneurysms, 7 patients had ruptured cerebral aneurysms associated with PKD. The authors retrospectively reviewed the database and imaging studies of such patients as sources for identification and analysis. RESULTS: All 7 patients presented with subarachnoid hemorrhage (SAH). One patient showed Hunt and Hess grade I, 4 of grade II, and 2 of grade III. Six patients showed Fisher group II and 1 patient of group III. Four aneurysms were located at anterior cerebral artery, 2 at middle cerebral artery, and 1 at internal carotid artery. Five patients had small aneurysms and the remaining 2 had large (diameter > or = 10 mm) aneurysms. All aneurysms were in saccular shape. Two of the 7 patients (28.6%) had multiple aneurysms. One patient suffered delayed ischemic neurological deficit. All patients were treated by microsurgery and showed favorable outcome (good: 7). CONCLUSIONS: The patients harboring PKD had high probability of hypertension. So, intact aneurysms in those patients were exposed to higher rate of being ruptured. Surgery was necessary for ruptured lesions, as well as unruptured lesions which size was increased at follow up imaging study. Multimodality management approach with nephrologist and neuroradiologist are very necessary. The ultimate management outcome was satisfactory.
