Randomized trail of nasal synchronized intermittent mandatory ventilation compared with nasal continuous positive airway pressure in preterm infants with respiratory distress syndrome.
- Author:
Wei-Wei GAO
1
;
San-Zhi TAN
;
Yun-Bin CHEN
;
Yong ZHANG
;
Yue WANG
Author Information
- Publication Type:Journal Article
- MeSH: Continuous Positive Airway Pressure; methods; Humans; Infant, Newborn; Infant, Premature; Intermittent Positive-Pressure Ventilation; methods; Respiratory Distress Syndrome, Newborn; therapy
- From: Chinese Journal of Contemporary Pediatrics 2010;12(7):524-526
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo compare the efficacy of nasal synchronized intermittent mandatory ventilation (nSIMV) and nasal continuous positive airway pressure (nCPAP) in preterm infants with respiratory distress syndrome (RDS).
METHODSFifty preterm infants with RDS who received pulmonary surfactant were randomized to nSIMV and nCPAP groups after extubation. Clinical signs, symptoms and blood gas results following nSIMV or nCPAP were compared in the two groups.
RESULTSCompared with the nCPAP group, the nSIMV group had a lower incidence of failure respiratory support (24% vs 60%; P<0.05), a lower incidence of hypercarbonia (12% vs 40%; P<0.05) and a lower incidence of hypoxia (24% vs 36%; P<0.05).
CONCLUSIONSnSIMV is more effective in respiratory support in preterm infants with RDS.
