Multi-variate regression analysis of clinicopathological characteristics and prognosis of colorectal cancer.
- Author:
Jian-ping WANG
1
;
Zu-li YANG
;
Lei WANG
;
Wen-guang DONG
;
Yi-hua HUANG
;
Jian-zhang QIN
;
Wen-hua ZHAN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Colorectal Neoplasms; diagnosis; mortality; pathology; Female; Humans; Male; Middle Aged; Multivariate Analysis; Neoplasm Staging; Prognosis; Regression Analysis; Survival Rate
- From: Chinese Journal of Oncology 2003;25(1):59-61
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the relationship between clinicopathologic features and prognosis of colorectal cancer after surgical treatment.
METHODSThe clinical characteristics, pathologic features and survival rate of 761 patients with colorectal cancer after surgical treatment were univariately and multivariately analyzed.
RESULTSThe overall 3- and 5-year survival rates of patients with colorectal cancer after surgical treatment were 62.9% and 60.7% with a median survival of 1,825 days. The factors of gross findings, degree of differentiation, infiltration, nodal and distant metastasis and neoplastic intestinal obstruction influenced the survival rate by univariate analysis. The factors of Dukes stage, gross tumor configuration, intramural spread and differentiation degree were available independent prognostic factors through multivariate analysis.
CONCLUSIONDukes stage, as the most important available independent prognostic factor (P < 0.0005), is able to assess the postoperative survival.
