Percutaneous hepatic puncture radio frequency ablation in the treatment of hepatocellular carcinoma.
- Author:
Yi CHEN
1
;
Meng-chao WU
;
Han CHEN
;
Zhi-jian ZHANG
;
Ye-tao GAO
Author Information
- Publication Type:Clinical Trial
- MeSH: Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; surgery; Catheter Ablation; Female; Humans; Liver Neoplasms; surgery; Male; Middle Aged; Punctures; Treatment Outcome
- From: Chinese Journal of Oncology 2003;25(1):88-90
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the curative effect of percutaneous radio frequency ablation (PRFA) on hepatocellular carcinoma.
METHODSUnder local or epidural anaesthesia, radio frequency electrodes were percutaneously introduced with ultrasound guide into the tumor in the liver for ablation.
RESULTSAmong the 96 hepatic cancer lesions in 60 patients, 41 (42.7%) with diameter < 3.5 cm were ablated by one session. The effective rate (CR + PR) was 100% (41/41) with CR 92.6% (38/41) and PR 7.3% (3/41). During the 6 - 24 month follow up of these lesions, 36 (87.8%) of these 41 patients showed no recurrence by CT or MRI. Fifty-five (57.3%) lesions with diameter 3.5 cm < or = Phi < 12 cm were ablated by two or three sessions, with CR 3.6% (2/55), PR 67.3% (37/55) and CR + PR 70.9% (39/55) by CT or MRI in 1 to 3 months after the treatment.
CONCLUSIONPercutaneous radio frequency ablation is effective on liver tumor with Phi < 3.5 cm. It is partly effective on lesions with 3.5 cm < or = Phi < 12 cm.
