Prognostic factors of epithelial ovarian cancer in young women.
- Author:
Rong ZHANG
1
;
Ling-ying WU
;
Wen-hua ZHANG
;
Hong-jun LI
;
Shu-min LI
;
Li-ying LIU
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Female; Humans; Middle Aged; Neoplasm Staging; Neoplasms, Glandular and Epithelial; mortality; pathology; therapy; Ovarian Neoplasms; mortality; pathology; therapy; Prognosis; Proportional Hazards Models; Survival Rate
- From: Chinese Journal of Oncology 2003;25(3):264-267
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the clinical characteristics, survival rate and prognosis of young patients with epithelial ovarian carcinoma.
METHODSThe clinic data of 455 women with epithelial ovarian carcinoma were reviewed. Kaplan-Meier method was used to calculate the survival rate. Cox proportional hazards regression model was used to determine the independent effect of each variable on survival.
RESULTSOf 445 patients with epithelial ovarian carcinoma, 92 were < or = 40 years of age and 363 were older. Higher incidence of early-stage, well differentiation and mucous cell type but lower incidence of serous cell type, ascites and residual tumors were found in the younger group. The overall 5-year survival rates were 79.55% in < or = 40 years group and 28.2% in > 40 years group (P < 0.001). Univariate analysis showed that the survival rate of patients < or = 40 years was significantly higher than that of > 40 years. Only age, stage and residual disease were found to be the significant independent prognostic factors by the multivariate analysis.
CONCLUSIONEpithelial ovarian carcinoma in patients with age
