Meta-analysis of the effectiveness of Chinese and Western integrative medicine on medium and advanced lung cancer.
- Author:
Shuo YANG
1
;
Meng CUI
;
Hai-Yan LI
;
Ying-Kai ZHAO
;
Yong-Hong GAO
;
Hai-Yan ZHU
Author Information
- Publication Type:Journal Article
- MeSH: Carcinoma; epidemiology; pathology; therapy; Combined Modality Therapy; Disease Progression; Humans; Integrative Medicine; methods; Lung Neoplasms; epidemiology; pathology; therapy; Medicine, Chinese Traditional; methods; Neoplasm Staging; Publication Bias; statistics & numerical data; Randomized Controlled Trials as Topic; statistics & numerical data; Treatment Outcome; Western World
- From: Chinese journal of integrative medicine 2012;18(11):862-867
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo summarize the effectiveness of Chinese and Western integrative medicine in treating medium and advanced lung cancer, and to provide guidelines for clinical application.
METHODSFor this metaanalysis, a comparative search of Chinese medicine data in Chinese National Knowledge Infrastructure (CNKI) and Chinese BioMedical Literature Database (CBM) was undertaken to identify articles related to randomized comparative research of Chinese and Western integrative medicine in treating medium and advanced lung cancer between 1996 to 2006. Quality of life (QOL) was estimated using RevMan 4.2 software for data processing, adopting the odd ratio (OR) and the 95% confidence interval (CI).
RESULTSThrough meta-analysis of 10 qualified articles, the results were as follows: the merging effectiveness of QOL [OR=3.80, 95% CI (2.65, 5.47)]; the rate of survival [OR=3.44, 95% CI (2.04, 5.80)]; the tumor response rate [OR=1.88, 95% CI (1.37, 2.58)]; the tumor developing rate [OR=0.33, 95% CI (0.23, 0.48)]. Significant differences existed between the Chinese and Western integrative medicine treatment group and the Western treatment group (P<0.01).
CONCLUSIONSChinese and Western integrative medicine treatment of medium and advanced lung cancer has shown to improve patients' QOL and survival rate; it also can control tumor development in the short term.
