Application of collagen hydrogel in cartilage tissue engineering.
- Author:
Zhi-gang NING
1
;
Liu YANG
Author Information
1. Southwest Hospital, Third Military Medical University of Chongqing, China.
- Publication Type:Journal Article
- MeSH:
Collagen;
Humans;
Hydrogel, Polyethylene Glycol Dimethacrylate;
Tissue Engineering;
methods
- From:
China Journal of Orthopaedics and Traumatology
2011;24(10):884-886
- CountryChina
- Language:Chinese
-
Abstract:
Articular osteocartilage injury caused by trauma or bone disease is very common in clinical practices,the proportion of cartilage defects reached 40.31%. As the low self healing abilities of articular cartilage, the technology of tissue engineering becomes a new method to treat articular cartilage injuries with regenerative medicine. Scaffolds can be divided into preformed and hydrogel scaffolds according to properties. The traditional graft of pre-formed scaffold will bring the secondary injury to the cartilage around the defect, and the loose graft intergration with the defect surface is still a problem. Repairing irregular articular cartilage defects with ideal biomimic materials on the basis of avoiding secondary damage will become a main issue. The method of minimally invasive injecting, biomimics, and in situ remodeling brings hope to articular cartilage repairing. Below is a summary of the international and domestics reference data of recent years on collagen hydrogel in cartilage tissue engineering.
