Research on liposoluble ingredients of Quchiling.
- Author:
Wen WENG
1
;
Fei XIAO
;
Xiaoguang LI
;
Qin GAO
;
Huanmin LUO
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Anisoles; chemistry; metabolism; Brain; metabolism; Cyclooctanes; chemistry; metabolism; Dioxoles; chemistry; metabolism; Drugs, Chinese Herbal; chemistry; metabolism; pharmacokinetics; Female; Gas Chromatography-Mass Spectrometry; Lignans; chemistry; metabolism; Male; Polycyclic Compounds; chemistry; metabolism; Rats; Rats, Sprague-Dawley
- From: China Journal of Chinese Materia Medica 2010;35(1):63-66
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the liposoluble ingredients of Quchiling (LQ), which enter the blood and the brain,and to confirm the active ingredients of LQ in vivo.
METHODSerum pharmacochemistry and gas chromatography mass spectroscopy were used to analyze ingredients of LQ entering the blood and the brain.
RESULTThere were eleven ingredients of LQ to enter the blood and six ingredients of LQ to enter the brain.
CONCLUSIONIt is confirmed that eleven ingredients of LQ entered the blood, which are beta-asarone, schisandrol A, schisandrol B, deoxyschisandrin, schisandrin B, schisantherrin A, schisantherrin B, schisantherrin C, delta-cadinene, delta-cadinol and calamendiol in the blood, and that six ingredients are beta-asarone, schisandrol A, schisandrol B, deoxyschisandrin, schisandrin B and calamendiol in the brain.
