Lactone constituents of Saussurea involucrata.

Author: Yi SHEN ¹ ; Jianhua ZOU ; Yingli MA ; Jungui DAI
Author Information

1. Key Laboratory of Biosynthesis of Natural Products, Ministry of Public Health, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Publication Type:Journal Article
MeSH: Chromatography; Lactones; chemistry; Magnetic Resonance Spectroscopy; Plant Extracts; chemistry; Saussurea; chemistry
From: China Journal of Chinese Materia Medica 2009;34(24):3221-3224
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo study the chemical constituents of Saussurea involucrata.
METHODCompounds were isolated and purified by column chromatography, and their structures were elucidated by chemical and spectroscopic methods.
RESULTEight compounds were yielded and identified as beta-sitosterol (1), dotriacontanoic acid (2), hexacosan-4-olide (3), (+)-11alpha, 13-dihydrodehydrocostuslactone (4), 8alpha-acetoxydehydrocostus lactone (5), zaluzanin C (6), 11,13beta-dihydrozaluzanin C (7), 8alpha-hydroxy-11beta-11,13-dihydrodehydrocostuslactone (8).
CONCLUSIONCompounds 2-7 were first isolated from S. involucrate.