Efficacy of Maixuekang capsule on reconvalescents of cerebral infarction and its impact on coagulation function.
- Author:
Yong-Xing YAN
1
;
Li-Zhen LIANG
;
Yong-Hui SHEN
;
Peng LI
;
Chang-Yang ZHONG
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Blood Coagulation; drug effects; Capsules; therapeutic use; Cerebral Infarction; drug therapy; metabolism; physiopathology; Drugs, Chinese Herbal; administration & dosage; adverse effects; Female; Fibrinogen; metabolism; Humans; Male; Prothrombin Time
- From: China Journal of Chinese Materia Medica 2012;37(23):3667-3668
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the clinical efficacy of Maixuekang capsule in reconvalescents of cerebral infarction and its impact on coagulation function.
METHODOne hundred and twenty cases of reconvalescents of cerebral infarction were randomly divided into treatment and control groups. The 50 cases in the control group were provided with conventional therapy, while the 70 cases in the treatment group were provided with the combination of conventional therapy and Maixuekang capsule for 3 months. Their neurological function and prothrombin time (PT), activated partial thromboplastin time (APTT) clotting enzyme time (TT), fibrinogen (Fib) were measured before and after treatment.
RESULTAfter the treatment, PT, APTT and TT were prolonged compared with those before the treatment in the treatment group (P<0.05), whereas Fib, neurological deficit scores decreased (P<0.01) and significantly different from the control group (P<0.05).
CONCLUSIONMaixuekang capsule is among safe and effective drugs in treatment of reconvalescents of cerebral infarction, and can improve the patient's coagulation state.
