Chemical constituents from Daphne acutiloba.
- Author:
Sheng-Zhuo HUANG
1
;
Qing-Yun MA
;
Yu-Qing LIU
;
Jun ZHOU
;
You-Xing ZHAO
Author Information
- Publication Type:Journal Article
- MeSH: Coumarins; chemistry; isolation & purification; Daphne; chemistry; Drugs, Chinese Herbal; chemistry; isolation & purification; Furans; chemistry; isolation & purification; Lignans; chemistry; isolation & purification; Mass Spectrometry
- From: China Journal of Chinese Materia Medica 2013;38(1):64-69
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents from Daphne acutiloba.
METHODThe constituents were separated by column chromatography, and their structures were elucidated by spectroscopic data analyses.
RESULTFifteen compounds were isolated from the EtOAc extract and identified as wikstroelide M (1), vesiculosin (2), prostratin (3), 7-hydroxy-coumarin (4), 7,8-di-hydroxy-coumarin (5), isodaphnoside (6), daphnorine (7), rutamontine (8), daphnolin (9), daphneticin (10), (+)-pinoresinol-beta-D-glucoside (11), oleodapnone (12), oleodaphnal (13), ergosterol peroxide (14) and cholest-5-en-3beta-ol (15).
CONCLUSIONAll the compounds except for 4, 5 and 14 were obtained from the stems of this plant for the first time.