Chemical constituents of Gentiana rhodantha.
- Author:
Yun CHEN
1
;
Guo-Kai WANG
;
Can WU
;
Min-Jian QIN
Author Information
- Publication Type:Journal Article
- MeSH: Chromatography, Gel; Chromatography, Reverse-Phase; Dextrans; Gentianaceae; chemistry; Mass Spectrometry; Oleanolic Acid; analogs & derivatives; chemistry; isolation & purification; Plant Extracts; chemistry; isolation & purification; Plants, Medicinal; chemistry; Quercetin; chemistry; isolation & purification; Salicylic Acid; chemistry; isolation & purification; Silica Gel; Triterpenes; chemistry; isolation & purification; Xanthones; chemistry; isolation & purification
- From: China Journal of Chinese Materia Medica 2013;38(3):362-365
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo determine the chemical constituents of Gentiana rhodantha.
METHODTo isolate the constituents, column chromatography over silica gel, MCI, Sephadex LH-20 and C18 reverse-phased silica gel were used. Spectroscopic methods were used to elucidate the structures of the isolated compounds.
RESULTSixteen compounds were isolated and elucidated as ten phonemic compounds, namely 1,3,7,8-tetrahydroxylxanthone (1), rhodanthenone D (2), 1,3,6,7-tetrahydroxylxanthone (3), 1,3,7-trihydroxy-4,8-dimethoxyxanthone (4), quercetin (5), isoorientin (6), mangiferin (7), norswertianolin (8), gallic acid ethyl ester (9) and salicylic acid (10), and six triterpenes including alpha-amyrin (11), erythrodiol 3-O-palmitate (12), ursolic aldehyde (13), uvaol 3-O-acetyl (14), ursolic acid (15) and 2alpha-hydroxyursolic acid (16).
CONCLUSIONCompounds 4-6, 8, 10-12, 15 and 16 were isolated from this plant for the first time. Compounds 1 and 3 were obtained firstly from the genus Gentiana and compounds 9, 13-14 were firstly from the family Gentianaceae.
