Effect of hydrostatic pressure on ultrastructure of synovial fibroblasts from rat temporomandibular joint.
- Author:
Meng-Jie WU
1
;
Jian-Ying FENG
;
Zhi-Yuan GU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Apoptosis; Fibroblasts; ultrastructure; Hydrostatic Pressure; Rats; Rats, Sprague-Dawley; Synovial Membrane; cytology; Temporomandibular Joint; cytology
- From: Chinese Journal of Stomatology 2008;43(12):754-755
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the role of apoptosis in the remodeling of temporomandibular joint (TMJ) under pressure.
METHODSSynovial fibroblasts obtained from rat temporomandibular joint were subjected to different hydrostatic pressure for 12 h. Changes of ultrastructure were observed by transmission electron microscope.
RESULTSAt 30 kPa, the ultrastructure of synovial fibroblasts showed no obvious changes. At 60 kPa, the chromatin was condensated, the baryon took on crescent and the mitochondria seemed varicose. At 90 kPa, the apoptosis-like body was wrapped by membrane and embedded in the high density chromatin.
CONCLUSIONSApoptosis-like change took place in ultrastructure of synovial fibroblasts under hydrostatic pressure, and the degree of the change was related to the hydrostatic pressure exerted.
