The study on pathogenesis of latex allergy..
- Author:
Ning LI
1
;
Bo CEHN
;
Yi-ping XU
;
Jian-hua WANG
;
Zu-qun WU
;
Han-bing ZOU
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Child; Child, Preschool; Female; Humans; Immunoglobulin E; blood; Infant; Latex Hypersensitivity; diagnosis; etiology; prevention & control; Male; Middle Aged; Occupational Diseases; diagnosis; etiology; prevention & control; Outpatients; Skin Tests; Young Adult
- From: Chinese Journal of Industrial Hygiene and Occupational Diseases 2005;23(1):50-52
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEIn order to study the pathogenesis of latex allergy and the significance in the prevention and cure of occupational diseases.
METHODS651 cases in the out-patient department were tested with skin prick test (SPT), and the specific IgE (sIgE) to latex were detected by means of disk ELISA and Western-blot.
RESULTSIt was found that the positive rate of latex SPT (37.5%) and sIgE (31.25%) were rather higher in patients in comparison with those of the normal. The positive rate of latex sIgE was much higher in the high-risk group than that of the low-risk group and the normal. The serum of the patients can react with multi-bands in the latex glove extracts.
CONCLUSIONThe prevalence of latex allergy is rather high, this disease is mediated by IgE. The people in high-risk should be tested by latex allergy in order to take proper occupational and daily protection.