Etiology and diagnosis of intellectual disability.
- Author:
Pu YANG
1
;
Bao-Heng GUI
;
Ling-Qian WU
Author Information
1. State Key Laboratory of Medical Genetics, School of Sciences, Central South University, Changsha 410078, China. wulingqian@sklmg.edu.cn.
- Publication Type:Journal Article
- MeSH:
Chromosome Banding;
High-Throughput Nucleotide Sequencing;
Humans;
Intellectual Disability;
diagnosis;
etiology;
genetics;
Microarray Analysis
- From:
Chinese Journal of Contemporary Pediatrics
2015;17(6):543-548
- CountryChina
- Language:Chinese
-
Abstract:
Intellectual disability, occurring in 1%-3% of the general population, is a common disease of the nervous system in children. Since diverse genetic and environmental factors contribute to its pathogenesis, the etiological diagnosis of intellectual disability is challenging with respect to the selection of diagnostic tests. It is important to determine the etiology of intellectual disability for the assessment of prognosis, treatment and the family plan. This paper summarizes the research progress in etiology and diagnosis for intellectual disability and introduces the recommended clinical genetics diagnostic approach from the American Academy of Pediatrics.
