Effect of processing parameters on the degradation of calcium polyphosphate bioceramic for bone tissue scaffolds.
- Author:
Yingjie QIN
1
;
Xixun YU
;
Yuanwei CHEN
;
Yulong DING
;
Changxiu WAN
Author Information
1. Department of Polymer Materials and Engineering, Sichuan University, Chengdu 610065, China.
- Publication Type:Journal Article
- MeSH:
Absorbable Implants;
Biocompatible Materials;
chemistry;
Bone Substitutes;
chemistry;
Calcium;
chemistry;
Calcium Phosphates;
chemistry;
Ceramics;
chemistry;
Polymers;
chemistry;
Polyphosphates;
chemistry;
Tissue Scaffolds;
chemistry
- From:
Journal of Biomedical Engineering
2007;24(4):794-797
- CountryChina
- Language:Chinese
-
Abstract:
This study was undertaken to elucidate the degradation regularity of calcium polyphosphate (CPP) scaffolds with different preparation parameters. CPP scaffolds with different main crystalline phases were prepared by controlling the particle size of the calcining stuff and the calcining heat. Specimens were soaked into Tris-buffer solution and simulated body fluid (SBF) for 60 days. Results show: alpha-CPP degrades faster than does beta-CPP, and beta-CPP degrades faster than does gamma-CPP; the lower the sinter temperature, the better the degradation of CPP morever, the degradation rate of CPP is inversely proportional to the original particle size. These data suggest that crystal type, sinter temperature and particle size influence the degradation rate of CPP markedly.
