Long circulation liposome and nuclear medicine.
- Author:
Chao MA
1
;
Anren KUANG
Author Information
1. Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Chemistry, Pharmaceutical;
methods;
Drug Carriers;
chemistry;
Drug Delivery Systems;
Drug Stability;
Genetic Therapy;
methods;
Humans;
Liposomes;
blood;
chemistry;
Nuclear Medicine;
methods;
Polyethylene Glycols;
chemistry;
Surface Properties
- From:
Journal of Biomedical Engineering
2007;24(4):941-945
- CountryChina
- Language:Chinese
-
Abstract:
Liposomes play an important role in drug delivery systems. However, conventional liposomes are short of active targeting ability and stability in blood circulation, which is required for efficient drugs delivery of interest. PEGs-containing liposomes are able to be stabilized in blood circulation for a longer period of time, able to be delivered properly in time and in amount to the targeted organs, and able to suppress the side effects of some drugs.
