Malignant Histiocytosis: A case report.
- Author:
Sook Tae HA
;
Gi Yeong HUH
;
Kang Suek SUH
;
Sun Kyung LEE
- Publication Type:Case Report
- MeSH:
Follow-Up Studies;
Biopsy
- From:Korean Journal of Pathology
1986;20(3):395-398
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We have recently experienced a clinically atypical case of malignant histiocytosis involving the spleen, ileum and bone marrow, in a 25-year-old Korean male. He was admitted to our hospital because of multiple purpuric lesions of skin which had been appearing since 2 years ago. Physical and laboratory examinations revealed marked splenomegaly with pancytopenia. With clinical impression of hypersplenism, splenectomy was performed. During the operation, the surgeons found a dark red mucosal lesion in the ileum incidentally, to resect the segment. Microscopic findings of the spleen and the ileal lesion showed extensive proliferation of atypical histiocytes, many of them phagocytosing numerous erythrocytes. Bone marrow biopsy was done for follow-up study, which showed increased cellularity with infiltration of atypical histiocytes.
