Investigation on security of colloidal bismuth subcitrate compound - Bimix capsules
- Author:
Quang Minh Do
- Publication Type:Journal Article
- Keywords:
Bimix
- MeSH:
Pharmaceutical Preparations;
toxicity
- From:Pharmaceutical Journal
1999;282(10):14-16
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The acute toxicity of Bimix (CBS) has been tested on mice at the dose of 1.25g/kg once time daily. This dose was equivalent to dose of 73 times the daily therapeutic dose on body weight. No toxic effects were seen. Acute toxicity appeared to be virtually nil. The semi-acute has also tested on mice at the dose 0.125g/kg once daily for 45 days. No accumulated toxicity was observed. No lesion or damage were apparent in the liver and kidneys. The results of experiment showed that CBS could be used for a long time with a little change on haematology and biochemical indices
