Perioperative management of orthopaedic patients with hemophilia A.
- Author:
Ying-guang WU
1
;
Xiao-guang LI
;
Kai-ning ZHANG
;
Yan-jun REN
;
Shu-feng LI
;
Mei-yuan LU
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Factor VIII; administration & dosage; Fractures, Bone; complications; surgery; Hemarthrosis; etiology; surgery; Hematoma; etiology; surgery; Hemophilia A; blood; complications; drug therapy; Humans; Male; Perioperative Care; Postoperative Complications; blood
- From: Chinese Journal of Surgery 2004;42(23):1430-1433
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo discuss the perioperative management of hemophiliacs A with orthopaedic complications.
METHODSTo regulate the injection of factor VIII concentrate in peroperative period by testing the level of factor VIII:C in 27 cases. The lever of factor VIII:C was improved to 30% - 50% at the day before the operation. To the severe patients, it was maintained at 58.5% - 89.3% during the operation and at 47.0% - 78.4% in postoperation. While to the gentle, it was maintained at 38.5% - 52.5% during the operation and at 29.2% - 52.3% in postoperation. The individualized surgical procedures were carried out, such as arthrocentesis, open knee synovectomy or arthroscopic synovectomy, evacuation or curettage of haematoma, debridements, internal fixation.
RESULTSAll patients were cured in 14 - 105 days by regulating the injection of factor VIII during the peroperative period. The usage of factor VIII was 1 200 - 70 250 IU.
CONCLUSIONWhile the hemophiliacs have orthopaedic complications, it is necessary to promise the factor VIII:C being maintained at the lever of hemostasis during the peroperative period. The hemophiliacs are endurable to the operation.
