Study on the changes of thrombosis-associated factors in patients with coronary heart disease of turbidity-phlegm blocking syndrome.
- Author:
Yun-long WANG
1
;
Dong-qing AN
;
Ning MA
;
Meng ZHU
;
Hong-yan SUN
Author Information
- Publication Type:Journal Article
- MeSH: Case-Control Studies; Coronary Disease; blood; physiopathology; Fibrin Fibrinogen Degradation Products; metabolism; Fibrinogen; analysis; Humans; Thrombosis; blood; physiopathology; von Willebrand Factor; metabolism
- From: Chinese journal of integrative medicine 2009;15(5):337-340
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo preliminarily explore the relationship between thrombosis and its associated factors in patients with coronary heart disease (CHD) of turbidity-phlegm blocking syndrome (TPB), and to study its acting mechanism.
METHODSPlasma levels of thrombosis-associated factors, including Von Willebrand factor: (vWF), D-dimer, and fibrinogen (Fg), in 85 patients of CHD with TPB, 93 with CHD of non-TPD, and 89 healthy persons were detected and compared.
RESULTSLevels of the three factors were increased in all the CHD: patients, and were higher in TPB patients than in non-TPB patients (P<0.01 or P<0.05).
CONCLUSIONThe TPB: syndrome in CHD patients was closely related to the blood coagulation-fibrinolytic system; they might be in pre-thrombosis state, and the plasma levels of vWF, D-dimer, and Fg could be taken as the objective indices for thrombosis differentiation of TPB syndrome in CHD patients.
