Preparation and in vitro release of Maiyanning sustained-release patches.
- Author:
Sumin YUAN
1
;
Jian NI
Author Information
- Publication Type:Journal Article
- MeSH: Chemistry, Pharmaceutical; Dosage Forms; Drugs, Chinese Herbal; chemistry; Kinetics; Solubility
- From: China Journal of Chinese Materia Medica 2009;34(13):1654-1657
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo prepare Maiyanning sustained-release patches and optimize the prescription.
METHODThe mono-factor design was used to screen the formulation of the sustained-release patches.
RESULTThe optimal composition of the formulation was MD-607 as the pressure sensitive adhesive and azone as the penetration enhancer with the content of 5.0%. Drugs released from the pressure-sensitive adhesive patches in a constant speed, it confirmed that the drug was released by zero order equation from the patches.
CONCLUSIONThe prepared patches have an ideal release trait.
