Alkaloids from Macleaya cordata.
- Author:
Fengzhi YE
1
;
Feng FENG
;
Wenyuan LIU
Author Information
- Publication Type:Journal Article
- MeSH: Alkaloids; chemistry; isolation & purification; Drugs, Chinese Herbal; chemistry; isolation & purification; Papaveraceae; chemistry
- From: China Journal of Chinese Materia Medica 2009;34(13):1683-1686
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the alkaloids of Macleaya cordata.
METHODThe alkaloids were isolated and purified by various column chromatography as well as recrystallization. Their structures were identified by physico-chemical properties and spectral analysis.
RESULTThirteen alkaloids were isolated and identified as 6-methoxy-dihydrosanguinarine (1), norsanguinarine (2), 6-acetonyl-dihyrochelerythrine (3), 6-acetonyl-dihyrosanguinnarine (4), sanguidimerine (5), chelidimerine (6), (+/-) -bocconarborine A (7), (+/-)-bocconarborine B (8), cryptopine (9), dihydrosanguinarine (10), dihydrochelerythrine (11), protopine (12), alpha-allocryptopine (13).
CONCLUSIONCompounds 2, 3, 5 - 9 were firstly isolated from the genus Macleaya and compound 1 was obtained from M. cordata for the first time.
