Chemical constituents from Xanthium mongolicum.
- Author:
Wenzhi ZHANG
1
;
Wei HAN
;
Ying LI
;
Shujun ZHANG
;
Defeng ZHAO
Author Information
- Publication Type:Journal Article
- MeSH: Drugs, Chinese Herbal; chemistry; isolation & purification; Xanthium; chemistry
- From: China Journal of Chinese Materia Medica 2009;34(13):1687-1689
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents of Xanthium mongolicum.
METHODThe compounds were isolated with column chromatography. The structures were determined by spectroscopic techniques.
RESULTEight compounds were isolated from X. mongolicum, four compounds are sesquiterpene lactones, two compounds are triterpenes and two compounds are lignins. Their structure elucidated as xanthatin (1), xanthinosin (2), 11alpha, 13-dihydroxanthatin (3), atractylenolide III (4), oleanolic acid (5), ursolic acid (6), lignocellulose (7), balanophonin (8).
CONCLUSIONCompounds 3-8 were isolated from this plant for the first time. Sesquiterpene lactones (1-3) had shown the induction hindrance activeness of the (ICAM-1), but the activitiy of 3 was weaker.
