Optimization of extraction technology of Psoralea corylifolia and Salvia miltiorrhiza by orthogonal design with multi-targets.

Author: Wen CHEN ¹ ; Shouying DU ; Yang LU
Author Information

1. School of Chinese Pharmacy, Beijing University of Traditonal Chinese Medicine, Beijing 100102, China.
Publication Type:Journal Article
MeSH: Chemical Fractionation; methods; Drugs, Chinese Herbal; chemistry; isolation & purification; Furocoumarins; chemistry; Organic Chemicals; chemistry; Salvia miltiorrhiza; chemistry
From: China Journal of Chinese Materia Medica 2009;34(14):1792-1794
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo optimize the extraction technology for Psoralea corylifolia and Salvia miltiorrhiza.
METHODAn orthogonal test was adopted in this study. The contents of Tanshinone IIA, Salvianolic acid B, Psoralen and Isopsoralen were used as indices of appraisal. Data processing was carried out with the multiple guidelines grading method for optimizing the extraction condition.
RESULTThe best extraction technology was to extract for 2 times with 8 fold ethanol solution (70%) and 1.5 h each time.
CONCLUSIONThe optimized extraction technology was rational and the extraction rate of the active principles is high.