Phenolic compounds from Galium aparine var. tenerum.
- Author:
Juan YANG
1
;
Xiaomei CAI
;
Shuzhen MU
;
Xiaosheng YANG
Author Information
- Publication Type:Journal Article
- MeSH: Drugs, Chinese Herbal; chemistry; isolation & purification; Galium; chemistry; Magnetic Resonance Spectroscopy; Mass Spectrometry; Phenols; chemistry; isolation & purification
- From: China Journal of Chinese Materia Medica 2009;34(14):1802-1804
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the compounds from the whole plant of Galium aparine var. tenerum.
METHODThe various column chromatographic techniques were applied to isolate the chemical constituents. MS, NMR and 2D-NMR spectroscopic techniques were uesd to identify chemical structures.
RESULTSix compounds were isolated from the EtOAc-soluble part of the 95% ethanol extract of the plant, and their chemical structures were identified as 1-(4-hydroxyphenyl)-ethanone (1), vanillic acid (2), 3,4-dihydroxybenzoic acid (3), p-hydroxycinnamic acid (4), gallic acid (5), 4-hydroxytruxillic acid (6).
CONCLUSIONThe NMR data of compound 6 were completely assigned by 2D-NMR techniques, including 1H-1H COSY, HMQC and HMBC spectra. This was the first time to report isolation of the compound 6 from natural product. The compounds 1-5 was isolated from the genus Galium for the first time.
