Steroids from Monascus purpureus metabolite.
- Author:
Xiaoya SHANG
1
;
Ruolan WANG
;
Suqin YIN
;
Jinjie LI
;
Zonglian JIN
Author Information
- Publication Type:Journal Article
- MeSH: Drugs, Chinese Herbal; chemistry; isolation & purification; metabolism; Monascus; chemistry; metabolism; Steroids; chemistry; isolation & purification; metabolism
- From: China Journal of Chinese Materia Medica 2009;34(14):1809-1811
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents of Monascus purpureus metabolite.
METHODThe compounds were isolated by column chromatography methods, and their structures were determined by spectroscopic methods.
RESULTEight compounds were isolated from the petroleum ether fraction of ethanolic extract and elucidated as stigmast-4-en-3-one (1), 3-oxo-24-methylenecycloarane (2), stigmasterol (3), 7beta-hydroxystigmasterol (4), 3beta-hydroxystigmast-5-en-7-one (5), 3beta-hydroxystigmast-5,22-dien-7-one (6), 5alpha, 8alpha-epidioxyergosta-6,22-dien-3beta-ol (7), sitosterol (8).
CONCLUSIONAll of the compounds were isolated from this genu for the first time except compound 3 and 7.
