Effect of auxiliary heterotopic partial liver transplantation on the pig with acute ischemic liver failure.
- Author:
Yong-xiang YI
1
;
Jian-guang YU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Female; Ischemia; surgery; Liver Failure, Acute; etiology; surgery; Liver Transplantation; methods; Male; Swine; Transplantation, Heterotopic; methods
- From: Chinese Journal of Hepatology 2003;11(4):232-234
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effect of auxiliary heterotopic partial liver transplantation on the pig with acute ischemic liver failure.
METHODSWhen portal vein was shrinked more than 85 percent and artery was ligated or reserved, auxiliary heterotopic partial liver transplantation was performed in the pigs. The living condition, liver function, blood supply, pathological change and bile secretion of donor liver were observed, analysed and summarized.
RESULTSIn the artery-ligated pigs, the volume of original liver reduced and the hepatocytes were necrotic evidently. While in the artery-reserved pigs, the colour and hepatocytes of original liver were normal. The volume of donor liver augmented, and the hepatocytes lived and proliferated well.
CONCLUSIONSLiver artery-ligated and portal vein-shrinker can result in acute ischemic liver failure, and auxiliary heterotopic partial liver transplantation is effective to treat this liver failure. reducing portal vein blood supply is little harmful to liver.
