Genetic imprinting and embryonic development.
- Author:
Li-jun YIN
1
;
He-feng HUANG
Author Information
1. The Affiliated Obstetrics and Gynecology HospitalìCollege of Medicine, Zhejiang University, Hangzhou, China.
- Publication Type:Journal Article
- MeSH:
Animals;
DNA Methylation;
DNA Modification Methylases;
genetics;
metabolism;
Embryonic Development;
genetics;
Genomic Imprinting;
genetics;
Humans;
Mutation
- From:
Journal of Zhejiang University. Medical sciences
2007;36(5):509-514
- CountryChina
- Language:Chinese
-
Abstract:
Erasure, establishment and maintenance of genetic imprinting are indispensable for normal embryonic development. All these processes depend on accurate expression and intimate cooperation of kinds of DNA methyltransferases. Many genetic syndromes and embryo developmental anomalies are caused by abnormality of genetic imprinting. Genetic imprinting is important for the nucleus totipotential of primordial germ cell, maturation of gamete,growth and development of embryo, structure and function of placenta as well as postnatal growth and development of individuals.
