Determination of residual organic solvents in Panax notoginseng extracts by capillary gas chromatography with headspace sampling.
- Author:
Han-hua WANG
1
;
Zhen-zhen NI
;
Tong-wei YAO
Author Information
- Publication Type:Journal Article
- MeSH: Chromatography, Gas; methods; Drug Contamination; prevention & control; Panax notoginseng; chemistry; Plant Extracts; analysis; Reproducibility of Results; Solvents; analysis
- From: Journal of Zhejiang University. Medical sciences 2007;36(6):598-603
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo develop a headspace gas chromatography method for the determination of residual organic solvents in Panax notoginseng extracts.
METHODSThe samples were injected into HP-INNOWAX capillary column by headspace sampler and analyzed with FID detector using standard addition method.
RESULTSThere was a good linearity in the experimental concentration (r=0.9932-0.9999). The rate of recovery was in the rang of 81.74%-111.2%. The numbers of theoretical plates were more than 15000 and the resolutions between the adjacent peaks were more than 2. The RSD of precision and accuracy were both less than 10 %.
CONCLUSIONThe method is simple,accurate and sensitive with good reproducibility, which can be used for the determination of the residual organic solvents in Panax notoginseng extracts.
