Blocking 1800 MHz mobile phone radiation-induced reactive oxygen species production and DNA damage in lens epithelial cells by noise magnetic fields.
- Author:
Wei WU
1
;
Ke YAO
;
Kai-jun WANG
;
De-qiang LU
;
Ji-liang HE
;
Li-hong XU
;
Wen-jun SUN
Author Information
- Publication Type:Journal Article
- MeSH: Cell Phone; Cells, Cultured; DNA; radiation effects; DNA Damage; radiation effects; Electromagnetic Fields; Epithelial Cells; metabolism; radiation effects; Humans; Lens, Crystalline; cytology; Microwaves; adverse effects; Radiation; Reactive Oxygen Species; metabolism
- From: Journal of Zhejiang University. Medical sciences 2008;37(1):34-38
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate whether the exposure to the electromagnetic noise can block reactive oxygen species (ROS) production and DNA damage of lens epithelial cells induced by 1800 MHz mobile phone radiation.
METHODSThe DCFH-DA method and comet assay were used respectively to detect the intracellular ROS and DNA damage of cultured human lens epithelial cells induced by 4 W/kg 1800 MHz mobile phone radiation or/and 2 muT electromagnetic noise for 24 h intermittently.
RESULT1800 MHz mobile phone radiation at 4 W/kg for 24 h increased intracellular ROS and DNA damage significantly (P<0.05). However, the ROS level and DNA damage of mobile phone radiation plus noise group were not significant enhanced (P>0.05) as compared to sham exposure group.
CONCLUSIONElectromagnetic noise can block intracellular ROS production and DNA damage of human lens epithelial cells induced by 1800 MHz mobile phone radiation.
