Effects of calcium phosphate cement/eucommia ulmoides extracts compound on cell proliferation and adhesion of MC3T3E1 osteoblasts in vitro.
- Author:
Jun LIN
1
;
You-qin LI
;
Wan-hong LI
;
Hong CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Alkaline Phosphatase; metabolism; Bone Cements; Calcium Phosphates; pharmacology; Cell Adhesion; radiation effects; Cell Differentiation; radiation effects; Cell Proliferation; radiation effects; Cells, Cultured; Gonadotropins; metabolism; Humans; Osteoblasts; cytology; drug effects; Tissue Adhesions
- From: Journal of Zhejiang University. Medical sciences 2008;37(1):78-82
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the effects of calcium phosphate cement/eucommia ulmoides extracts compound (CPC/EUE) on cell proliferation and adhesion of MC3T3E1 osteoblasts in vitro.
METHODSCultured MC3T3E1 osteoblasts were divided into 5 groups: blank control, CPC/EUE 0, 0.152, 0.304 and 0.608 mg/ml. 3H-TdR and scan electronic microscopy (SEM) were used to observe the cell growth, proliferation and adhesion.
RESULTThe CPC/EUE compound enhanced the cell growth, proliferation and adhesion. The concentrations of 0.152 mg/ml, 0.304 mg/ml were more significant in enhancing the cell proliferation rate (P<0.05).
CONCLUSIONCPC/EUE can promote the cell growth, proliferation and adhesion of the osteoblasts.
